The Protégé (the working title was The Asset) is centered on the story of a young woman named Anna (Maggie Q), saved as a child by the legendary assassin Moody (Samuel L. Jackson) and trained to become one of the the best paid assassins in the world.

When Moody is murdered, Anna searches for the killer to get revenge and everything turns into a game of seduction and domination against an enigmatic killer (Michael Keaton).